Condensation Approach to Aliphatic Oligourea Foldamers: Helices with N‐(Pyrrolidin‐2‐ylmethyl)ureido Junctions
Identifieur interne : 002574 ( Main/Exploration ); précédent : 002573; suivant : 002575Condensation Approach to Aliphatic Oligourea Foldamers: Helices with N‐(Pyrrolidin‐2‐ylmethyl)ureido Junctions
Auteurs : Juliette Fremaux [France] ; Lucile Fischer [France] ; Thomas Arbogast [France] ; Brice Kauffmann [France] ; Gilles Guichard [France]Source :
- Angewandte Chemie International Edition [ 1433-7851 ] ; 2011-11-25.
English descriptors
- Teeft :
- Aliphatic oligourea foldamers, Aliphatic oligoureas, Angew, Chem, Convergent condensation, Crystal structures, Foldamers, Guichard, Helical, Helical structure, Helix, Long helical segments, Main chain, Oligourea foldamers, Oligoureas, Proline, Proline residues, Pyrrolidine, Pyrrolidine junction, Pyrrolidine ring, Pyrrolidine unit, Pyrrolidine units, Segment junctions, Short oligoureas, Succinimidyl carbamate, Urea, Verlag gmbh, Weinheim angew.
Abstract
Caught in a fold: A simple and efficient coupling strategy to make aliphatic oligourea foldamers is reported. Crystal structures show that the pyrrolidine units (red; see picture) do not impair the 2.5‐helical folding of the oligoureas. This modular strategy enables assembly of long helical segments containing non‐adjacent pyrrolidine units as exemplified by the synthesis of a helix that is approximately 40 Å long.
Url:
DOI: 10.1002/anie.201105416
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 000414
- to stream Istex, to step Curation: 000414
- to stream Istex, to step Checkpoint: 000503
- to stream Main, to step Merge: 002599
- to stream Main, to step Curation: 002574
Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Condensation Approach to Aliphatic Oligourea Foldamers: Helices with N‐(Pyrrolidin‐2‐ylmethyl)ureido Junctions</title><author><name sortKey="Fremaux, Juliette" sort="Fremaux, Juliette" uniqKey="Fremaux J" first="Juliette" last="Fremaux">Juliette Fremaux</name></author><author><name sortKey="Fischer, Lucile" sort="Fischer, Lucile" uniqKey="Fischer L" first="Lucile" last="Fischer">Lucile Fischer</name></author><author><name sortKey="Arbogast, Thomas" sort="Arbogast, Thomas" uniqKey="Arbogast T" first="Thomas" last="Arbogast">Thomas Arbogast</name></author><author><name sortKey="Kauffmann, Brice" sort="Kauffmann, Brice" uniqKey="Kauffmann B" first="Brice" last="Kauffmann">Brice Kauffmann</name></author><author><name sortKey="Guichard, Gilles" sort="Guichard, Gilles" uniqKey="Guichard G" first="Gilles" last="Guichard">Gilles Guichard</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:99E0ECACECA926760250E8B55F1BF7AEA56C0078</idno><date when="2011" year="2011">2011</date><idno type="doi">10.1002/anie.201105416</idno><idno type="url">https://api.istex.fr/ark:/67375/WNG-NH8JNCMB-H/fulltext.pdf</idno><idno type="wicri:Area/Istex/Corpus">000414</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">000414</idno><idno type="wicri:Area/Istex/Curation">000414</idno><idno type="wicri:Area/Istex/Checkpoint">000503</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">000503</idno><idno type="wicri:doubleKey">1433-7851:2011:Fremaux J:condensation:approach:to</idno><idno type="wicri:Area/Main/Merge">002599</idno><idno type="wicri:Area/Main/Curation">002574</idno><idno type="wicri:Area/Main/Exploration">002574</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main">Condensation Approach to Aliphatic Oligourea Foldamers: Helices with N‐(Pyrrolidin‐2‐ylmethyl)ureido Junctions</title><author><name sortKey="Fremaux, Juliette" sort="Fremaux, Juliette" uniqKey="Fremaux J" first="Juliette" last="Fremaux">Juliette Fremaux</name><affiliation wicri:level="1"><country xml:lang="fr">France</country><wicri:regionArea>Université de Bordeaux‐CNRS UMR5248, Institut Européen de Chimie et Biologie, 2 rue Robert Escarpit</wicri:regionArea><wicri:noRegion>2 rue Robert Escarpit</wicri:noRegion><wicri:noRegion>2 rue Robert Escarpit</wicri:noRegion></affiliation></author><author><name sortKey="Fischer, Lucile" sort="Fischer, Lucile" uniqKey="Fischer L" first="Lucile" last="Fischer">Lucile Fischer</name><affiliation wicri:level="1"><country xml:lang="fr">France</country><wicri:regionArea>Université de Bordeaux‐CNRS UMR5248, Institut Européen de Chimie et Biologie, 2 rue Robert Escarpit</wicri:regionArea><wicri:noRegion>2 rue Robert Escarpit</wicri:noRegion><wicri:noRegion>2 rue Robert Escarpit</wicri:noRegion></affiliation></author><author><name sortKey="Arbogast, Thomas" sort="Arbogast, Thomas" uniqKey="Arbogast T" first="Thomas" last="Arbogast">Thomas Arbogast</name><affiliation wicri:level="1"><country xml:lang="fr">France</country><wicri:regionArea>Université de Bordeaux‐CNRS UMR5248, Institut Européen de Chimie et Biologie, 2 rue Robert Escarpit</wicri:regionArea><wicri:noRegion>2 rue Robert Escarpit</wicri:noRegion><wicri:noRegion>2 rue Robert Escarpit</wicri:noRegion></affiliation></author><author><name sortKey="Kauffmann, Brice" sort="Kauffmann, Brice" uniqKey="Kauffmann B" first="Brice" last="Kauffmann">Brice Kauffmann</name><affiliation wicri:level="1"><country xml:lang="fr">France</country><wicri:regionArea>Université de Bordeaux‐CNRS UMS3033, Institut Européen de Chimie et Biologie</wicri:regionArea><wicri:noRegion>Institut Européen de Chimie et Biologie</wicri:noRegion><wicri:noRegion>Institut Européen de Chimie et Biologie</wicri:noRegion></affiliation></author><author><name sortKey="Guichard, Gilles" sort="Guichard, Gilles" uniqKey="Guichard G" first="Gilles" last="Guichard">Gilles Guichard</name><affiliation wicri:level="1"><country xml:lang="fr">France</country><wicri:regionArea>Université de Bordeaux‐CNRS UMR5248, Institut Européen de Chimie et Biologie, 2 rue Robert Escarpit</wicri:regionArea><wicri:noRegion>2 rue Robert Escarpit</wicri:noRegion><wicri:noRegion>2 rue Robert Escarpit</wicri:noRegion></affiliation><affiliation wicri:level="1"><country wicri:rule="url">France</country></affiliation><affiliation wicri:level="1"><country xml:lang="fr">France</country><wicri:regionArea>Correspondence address: Université de Bordeaux‐CNRS UMR5248, Institut Européen de Chimie et Biologie, 2 rue Robert Escarpit</wicri:regionArea><wicri:noRegion>2 rue Robert Escarpit</wicri:noRegion><wicri:noRegion>2 rue Robert Escarpit</wicri:noRegion></affiliation></author></analytic><monogr></monogr><series><title level="j" type="main">Angewandte Chemie International Edition</title><title level="j" type="alt">ANGEWANDTE CHEMIE INTERNATIONAL EDITION</title><idno type="ISSN">1433-7851</idno><idno type="eISSN">1521-3773</idno><imprint><biblScope unit="vol">50</biblScope><biblScope unit="issue">48</biblScope><biblScope unit="page" from="11382">11382</biblScope><biblScope unit="page" to="11385">11385</biblScope><biblScope unit="page-count">4</biblScope><publisher>WILEY‐VCH Verlag</publisher><pubPlace>Weinheim</pubPlace><date type="published" when="2011-11-25">2011-11-25</date></imprint><idno type="ISSN">1433-7851</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">1433-7851</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="Teeft" xml:lang="en"><term>Aliphatic oligourea foldamers</term><term>Aliphatic oligoureas</term><term>Angew</term><term>Chem</term><term>Convergent condensation</term><term>Crystal structures</term><term>Foldamers</term><term>Guichard</term><term>Helical</term><term>Helical structure</term><term>Helix</term><term>Long helical segments</term><term>Main chain</term><term>Oligourea foldamers</term><term>Oligoureas</term><term>Proline</term><term>Proline residues</term><term>Pyrrolidine</term><term>Pyrrolidine junction</term><term>Pyrrolidine ring</term><term>Pyrrolidine unit</term><term>Pyrrolidine units</term><term>Segment junctions</term><term>Short oligoureas</term><term>Succinimidyl carbamate</term><term>Urea</term><term>Verlag gmbh</term><term>Weinheim angew</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Caught in a fold: A simple and efficient coupling strategy to make aliphatic oligourea foldamers is reported. Crystal structures show that the pyrrolidine units (red; see picture) do not impair the 2.5‐helical folding of the oligoureas. This modular strategy enables assembly of long helical segments containing non‐adjacent pyrrolidine units as exemplified by the synthesis of a helix that is approximately 40 Å long.</div></front></TEI><affiliations><list><country><li>France</li></country></list><tree><country name="France"><noRegion><name sortKey="Fremaux, Juliette" sort="Fremaux, Juliette" uniqKey="Fremaux J" first="Juliette" last="Fremaux">Juliette Fremaux</name></noRegion><name sortKey="Arbogast, Thomas" sort="Arbogast, Thomas" uniqKey="Arbogast T" first="Thomas" last="Arbogast">Thomas Arbogast</name><name sortKey="Fischer, Lucile" sort="Fischer, Lucile" uniqKey="Fischer L" first="Lucile" last="Fischer">Lucile Fischer</name><name sortKey="Guichard, Gilles" sort="Guichard, Gilles" uniqKey="Guichard G" first="Gilles" last="Guichard">Gilles Guichard</name><name sortKey="Guichard, Gilles" sort="Guichard, Gilles" uniqKey="Guichard G" first="Gilles" last="Guichard">Gilles Guichard</name><name sortKey="Guichard, Gilles" sort="Guichard, Gilles" uniqKey="Guichard G" first="Gilles" last="Guichard">Gilles Guichard</name><name sortKey="Kauffmann, Brice" sort="Kauffmann, Brice" uniqKey="Kauffmann B" first="Brice" last="Kauffmann">Brice Kauffmann</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/MersV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002574 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 002574 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= MersV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= ISTEX:99E0ECACECA926760250E8B55F1BF7AEA56C0078
|texte= Condensation Approach to Aliphatic Oligourea Foldamers: Helices with N‐(Pyrrolidin‐2‐ylmethyl)ureido Junctions
}}
| This area was generated with Dilib version V0.6.33. |  |